B12 injections are recommended for those who have a deficiency
The proposed mechanism for hyperhomocysteinaemia on inducing endothelial dysfunction and thus atherosclerosis includes homocysteine-induced endoplasmic reticulum stress, oxidative stress, and proinflammatory response.48 Animal models of hyperhomocysteinaemia have confirmed the causal relationship between hyperhomocysteinaemia and the development of endothelial dysfunction and accelerated atherosclerosis.48 Although meta-analyses have shown reduction of cardiovascular risk with reduction of homocysteine levels,46 47 vitamin supplementation (with vitamin B 6 , vitamin B 12 , and folic acid) to lower homocysteine in the body may not be transformed into clinically beneficial vascular outcomes
While B12 injections can be beneficial for a wide range of athletes, they may be particularly advantageous for: Vegan and Vegetarian Athletes: Plant-based diets can be low in B12, making supplementation crucial
Additional information Peer review information Nature Metabolism thanks Dominique Langin and the other, anonymous reviewers for their contribution to the peer review of this work
Methionine assists in the breakdown of fats in the body, thereby preventing the buildup of fatty deposits in the blood vessels which cause coronary artery disease and blockages in other parts of the body including the neck and legs
Produttori dal 1979 Chi Siamo LO.P
