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Healthcare providers prescribing AOD-9604 for joint health are doing so based on preclinical research evidence and clinical judgment, not FDA-approved indications
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Specically, path A is inactive because the energy barrier associated with direct dissociation of the methyl ligand is higher than the barrier of intersection between two dierent electronic states: a metal-to-ligand charge transfer state (MLCT), and a ligand eld state (LF) along the CoO coordinate of the S 1 PES