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Considerations in Medicine
1520% rings were extrapolated to 100% rings using the calculation suggested by Cappadoro et al
Imaging and biomarker assessments (such as for inflammation or cartilage changes) are typically missing, leaving the underlying mechanisms uncertain
When to absolutely discard expired medication Certain situations demand immediate disposal regardless of how close to or past the BUD: Any visible cloudiness, particles, or color change Vial was frozen at any point Extended exposure to temperatures above 30C (86F) More than 21 cumulative days at room temperature Unusual smell from the vial More than 7 days past the assigned BUD For comparison, the same principles apply to using expired semaglutide and other compounded GLP-1 medications
Y-jG: Formal analysis, Investigation, Writing original draft