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This extreme reactivity is due to its small size and lack of charge, allowing rapid diffusion across cellular structures

doi:10.1100/tsw.2009.137 Gupta A, Vij G, Sharma S, Tirkey N, Rishi P, Chopra K (2009) Curcumin, a polyphenolic antioxidant, attenuates chronic fatigue syndrome in murine water immersion stress model

It affects how your liver processes many medications, including some used alongside GLP-1s

Intake of sweet foods also decreases in the peri-ovulatory period (42) and protein intake increases in the luteal phase (43)

Still, the economics are unresolved