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Use AM and/or PM

As a result, 8-isoprostane, a biomarker of lipid peroxidation, is elevated in the exhaled breath condensate in adults and children with asthma [20]

This results in a surge of O 2 and opening of the mitochondrial permeability transition pore, triggering collapse of the mitochondrial membrane potential, release of pro-apoptotic factors, and massive hepatocyte necroptosis [367]

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