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Interestingly, while GSH declines in fibrosis, cysteine levels are elevated, suggesting that reduced GSH is primarily due to enzyme dysfunction rather than substrate deficiency [123]

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Tirzepatide is a 39amino acid dual incretin receptor agonist that activates both GLP1 and GIP receptors, enhancing glucosedependent insulin secretion, suppressing glucagon, slowing gastric emptying, and reducing appetite [1] [2]