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Current evidence is mixed and limited

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Allow vial contents to reach room temperature before reconstitution

Neurological symptom recovery , such as relief from tingling or "brain fog," may take longer as nerves require time to heal

CD36 expression in the sciatic nerve is upregulated in the absence of PCSK9, accompanied by increased cholesterol and TG levels and LDs accumulation, culminating in peripheral nerve lipid overload, mitochondrial dysfunction, and the onset of sensory neuropathy

Heliyon 9, e15756