The classical model of Nrf2 activation involved the direct OS-induced Keap-1 modification (Itoh et al., 2004)
Statistics and reproducibility Descriptive statistics included proportions for categorical variables and using medians and interquartile ranges (IQRs) for continuous variables
For people with hyperpigmentation, this shift produces a visible improvement in overall tone and reduces the contrast between affected and unaffected areas
doi:10.1016/j.rasd.2019.02.001 91. Oeltzschner, G., Chan, K
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