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The potential of GLP-1 receptor agonists to enhance cognitive function, reduce addictive behaviors, and alleviate depressive symptoms makes them a powerful area of study in neuroscience and psychiatry

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R01DK121619 to G.A.M

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A study assessing the acute effect of liraglutide in vagotomized subjects did implicate the vagus nerve in mediating the appetite effect (188), but the sample size in the study was small and subjects had a very low appetite at baseline, making it difficult to draw conclusions