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And why is that

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Indeed, these compounds exert numerous pleiotropic actions that favorably affect metabolism and diabetes comorbidities, showing an additional effect beyond glucose control

Also, these adverse outcomes directly or indirectly enhance oxidative stress, ultimately causing arrhythmias, cardiac hypertrophy, myocardial fibrosis, cardiac insufficiency, and HF

The biological effects of fibrin-binding synthetic oligopeptides derived from fibronectin on osteoblast-like cells

The present study aimed to investigate, in a murine model, the antidiabetic efficacy of cholic-acid-7-sulfate (CA7S) alone or in combination with sitagliptin