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Gastrointestinal adverse events and weight reduction in people with type 2 diabetes treated with tirzepatide in the SURPASS clinical trials

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1-MX is an adenosine receptor antagonist and increases the release and survivability of neurotransmitters

Identification of predictive biomarkers, including GLP1R and FTO variants as noted above, could further guide personalized agent selection in this genetically heterogeneous population

They also help minimise discomfort and prevent complications, though they work best when combined with professional care

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