somerae : Cetobacterium somerae dgat2 : Diacylglycerol O-acyltransferase 2 fasn : Fatty acid synthase G3P: Glyceraldehyde-3-phosphate GAM: Gifu anaerobic medium GAPDH: Glyceraldehyde-3-phosphate dehydrogenase glut4 : Glucose transporter 4 H&E: Hematoxylin and eosin hk : Hexokinase hsl : Hormone-sensitive lipase HSI: Hepatosomatic index ir : Insulin receptor mTOR: Mammalian target of rapamycin NEFA: Non-esterified fatty acid OA: Oleic acid p-AMPK: Phospho-adenosine 5-monophosphate (AMP)-activated protein kinase pfk : Phosphofructokinase pk : Pyruvate kinase PI3K: Phosphoinositide 3-kinase p-S6: Phospho-ribosomal S6 p-S6K: Phospho-ribosomal S6 kinase S6K: Ribosomal S6 kinase S6: Ribosomal S6 TC: Total cholesterol TG: Triglyceride VK2: Vitamin K 2 WB: Western blotting References Luo Y, Li M, Wang T, Zhou NN, Qiao F, Du ZY, et al
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50% of those with daily OAB episodes improved
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Central actions of GPR55 seem to rely on its ability to modulate intracellular Ca 2+ presynaptically and boost neurotransmitter release, as observed in the hippocampal CA1 to CA3 subregions of mice brain slices [153]
