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Additionally, nausea and early satiety may cause patients to rely on easily tolerated but nutritionally limited foods, potentially narrowing dietary diversity

In Traditional Chinese Medicine (TCM), Coptis is classified as a bitter, cold herb used to reduce heat conditions such as high fever, restlessness, and inflammation

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Animal research has reported changes in circadian hormone measurements, ageing-related markers, tumour outcomes and lifespan in selected models

PLoS One 11 , e0167844 (2016)

Among them, NF-B, Nrf2, SIRT1, PI3K/AKT/mTOR and JAK/STAT are the key ways for future pharmacological research of catalpol