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First, cytoskeletal remodeling supports neurite outgrowth and neuronal survival , and T4 has been shown to promote these by upregulating the cell-adhesion molecule L1

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The supernatants containing epithelial cells were collected and washed once with sterile cold PBS for RNA isolation, immunoblotting, or flow cytometry

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Research has shown that weekly injections at higher doses may promote fracture healing to a similar extent as daily lower-dose injections in rodent models, though human verification of weekly protocols is still in progress