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The use of these technologies alleviates notable barriers, such as injection discomfort and dosing schedule frequency, which have enhanced general therapy compliance and satisfaction

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Overall, these findings suggests that under pharmacologically relevant conditions, GLP-1R agonists that induce less internalization achieve greater maximal insulin release

The index date was defined as the date of the first documented SUD diagnosis during the observation period

Gastrointestinal side effects also amplify, potentially leading to severe nausea, vomiting, or inadequate nutrition