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The projected 18% reduction in cardiovascular events in persons who are overweight or are obese but without cardiovascular disease compares favorably to the recently announced top line results of the SELECT trial which studied Wegovy in persons with cardiovascular disease and showed an actual 20% reduction in future cardiovascular events

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Clinical trials are typically short in duration, highly controlled, and often exclude individuals with histories of depression, anxiety, or suicidal ideation

Our analysis of how quickly tirzepatide works breaks down the timeline in detail

But they work best when they are paired with the habits that support long-term results

People who were sitting on the sidelines