340-OR: LY3437943 (LY), a Novel Triple GIP/GLP-1/Glucagon Receptor Agonist, Provides Glucose Lowering and Weight Loss in Patients with T2DM after 12 Weeks of Treatment Multi-receptor incretin agonists are being developed with the goal of treating various metabolic diseases
N Engl J Med (2017) 376(18):174861
Moreira da Silva Guimares S, de Souza Cruz WM, de Souza Weigert G, Scalco FB, Colafranceschi AS, Ribeiro MG, et al
This upstream mechanism helps maintain more natural signaling patterns and may carry different risk and benefit profiles than direct growth hormone injections
Frontiers in Cell and Developmental Biology , 12
However, the market faces challenges, including the need for stronger clinical validation, varying patient responses, and the importance of clear guidance on proper use alongside GLP-1 therapies