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We do not know if the body needs a constant supply of the peptide to heal, or if a quick pulse is enough to trigger a self-sustaining healing process

Bull Exp Biol Med 2001;131:28592

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As outcome, we computed the free energy surfaces and transition probabilities

The highest dose outperformed liraglutide, which was notable because liraglutide was, at the time, a leading GLP-1 obesity treatment

Versus retinol and retinoic acid (cosmetic anti-ageing reference): retinol acts via RAR/RXR receptors and transcriptional modulation but with irritating effects (desquamation, solar sensitivity)