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The data mentioned and discussed in this Substack are publicly available.

03The endpoint determines what the trial proved The semaglutide result becomes more useful when each endpoint is separated

The peptide also increases integrin expression in basal keratinocytes at concentrations of 0.1-10 micromolar, enhancing p63 positivity, a transcription factor that maintains stem cell characteristics

However, later trials using the same probiotic formulation were unable to demonstrate the same beneficial effect (Lieske 2010

doi: 10.1016/S0140-6736(02)07952-7 64

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