Injections are particularly appropriate for those with: Pernicious anaemia, an autoimmune condition affecting B12 absorption Conditions affecting the stomach or small intestine, such as Crohns disease or coeliac disease Those who have had gastric surgery or bariatric procedures Strict vegans and vegetarians not meeting their B12 needs through food or oral supplements For those who can absorb B12 normally, oral supplements are generally an effective and well-evidenced alternative to injections
These include methionine (an essential amino acid involved in metabolism), inositol (a sugar alcohol involved in fat removal), and choline (an amine involved in the metabolism of fat)
However, by consuming various B12 sources you can achieve the recommended daily intake without trouble
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SURMOUNT-1 showed average weight loss of 21.4% at 10mg over 72 weeks
This finding has important safety implications, as elevated IGF-1 levels associated with full GH therapy raise concerns about increased cancer risk, particularly for individuals with pre-existing malignancies or strong family histories
