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It effectively kicked off the prohibition and criminalisation of these substances

In this context, the study of MCSs has become an area of considerable importance to understand the spatial architecture of signalling, with recent reports recognising their prominent role in pancreatic -cells for key processes ranging from insulin granule biogenesis to calcium homoeostasis 62,63,64

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These may include rash, pruritus, urticaria, and anaphylaxis