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Since the discovery of the satellite cell 50 years ago, research has provided valuable insights into the molecular mechanisms that regulate the satellite cell pool and ultimately the potential for regenerative myogenesis [5, 6]

Now, the mitigation strategies are clear enough: high-protein intake to spare muscle, and resistance training to preserve or build lean mass alongside the medication

PMID: 39247248

49 Similarly, higher BMI has detrimental effects on perceived health in HFrEF, which is also highly significant in HFpEF