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The Janus kinase-signal transducer and activator of transcription (JAK-STAT) signaling pathway ( Figure 2 ), on the other hand, was the first to be recognized as being pivotal in regulating a variety of aspects of human immunity, such as the control of inflammation and the activation of diverse leukocytes like neutrophils and macrophages (138)

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Glutathione depletion has been shown to affect mitochondrial function probably via selective inhibition of mitochondrial complex I activity

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