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Tirzepatide, a dual GLP-1 and GIP receptor agonist, slows stomach emptying to regulate appetite and blood sugara mechanism that may cause heartburn or reflux in roughly 10-15% of early users

The protective effects of liraglutide against A-induced neurotoxicity in neuroblastoma cells are attributed to the activation of the phosphoinositide 3-kinase (PI3K)/Akt signaling pathway, as evidenced by the increased phosphorylation of Akt and the altered expression of the apoptosis-related proteins Bcl-2/Bax, and cytochrome c [49]

DPP-4 inhibitors are implemented into the treatment algorithms of type 2 diabetes in many national and international guidelines (12)

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