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The research basethough extensive, comprising over 100 published studiesis entirely preclinical (animal models and in vitro experiments)

Al Ani A, Qureshi PAAA, Bollineni VR Cureus 2023

PLoS One 6 , e27488 (2011)

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Abnormal blood vessels in the esophagus, stomach, or duodenum Conditions such as esophageal varices or gastric varices, which are enlarged and fragile blood vessels, can cause bleeding and result in black, tarry stools