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Heparanase: A potential new factor involved in the renal epithelial mesenchymal transition (EMT) induced by ischemia/reperfusion (I/R) injury

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Thus dosage, pharmacokinetics, long-term safety, off-target effects in humans remain unknown

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Accordingly, the following sections examine the interplay between ferroptosis and inflammation and its disease-specific roles in atherosclerosis, myocardial ischemiareperfusion (I/R) injury, cardiomyopathies, heart failure and hypertention, among others

One patient in the KD group experienced a serious adverse event during the home phase: deep vein thrombosis/pulmonary embolism