G6PD deficiency can be life-threatening, especially in newborns, leading to bilirubin-induced neurological injury and bilirubin encephalopathy (kernicterus) and even to death 10,11,12,13,14,15
We do not know what fraction reaches systemic circulation in humans, and "detectable GI effect" does not equal "adequate systemic bioavailability for joint repair." The acetate salt versus free acid labeling problem
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Putative protective role of autoantibodies against the insulin-like growth factor-1 receptor in Graves disease: results of a pilot study