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Am J Physiol Gastrointest Liver Physiol 292(3):G849G856

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This is corroborated by in vitro studies, wherein cultured human islets exposed to high glucose were observed to secrete IL-1, with production increasing due to autocrine feedback (47)

It's a synthetic peptide, a short chain of 15 amino acids, derived from a protective protein found naturally in human gastric juice

Common reasons include: Pernicious anemia , an autoimmune condition affecting intrinsic factor production Gastrointestinal disorders, such as Crohns disease or celiac disease Prolonged use of certain medications, like proton pump inhibitors Knowing these causes helps spot at-risk people

Always follow with a moisturiser to protect your skin barrier