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doi: 10.1074/jbc.274.34.24408 73 OGormanDBCostelloMWeissJFirthSMScottCD

Alternating phases allows pathways to reset and may help maintain effectiveness over time

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Once on the matrix side of the membrane, the fatty acid is transferred to coenzyme A (CoA) and is then oxidized for energy production

Many patients achieve their weight loss goals at 1.0 to 1.7 milligrams (10-17 units) and maintain that dose indefinitely rather than advancing to the maximum