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It should also be kept in mind that, even in clinical situations in which it is mandatory to achieve rapid weight loss (e.g., cases of severe obesity in which major surgery, including bariatric surgery, is indicated) the patient very often is already affected by cardiovascular comorbidities [128], representing, per se, a specific contraindication to the use of pseudoephedrine or congeners

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[DOI] [PMC free article] [PubMed] [Google Scholar] 195.Stubbs B.J., Cox P.J., Evans R.D., Cyranka M., Clarke K., de Wet H