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That damage produces free radicals, which can create even more cell damage

Acta Pharm Sin B 12(2):708722

However, the brain is particularly vulnerable to oxidative damage due to the high levels of unsaturated lipids, oxygen, redox metal ions, and relatively poor antioxidant systems

In contrast, the intranasal route enhanced the distribution of insulin to the olfactory bulb with minimal systemic exposure of insulin

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It offers a versatile means of identifying the genetic connections among multiple cells within human tissues, exploring fundamental aspects of mitochondrial genetics, and facilitating multi-omic discoveries [25]