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SURMOUNT-2: tirzepatide with type 2 diabetes The second trial focused on adults who had both obesity and type 2 diabetes, a population that traditionally loses less weight with GLP-1 medications because insulin resistance and metabolic dysfunction create additional barriers

As a result, the pancreas compensates by producing more insulin to maintain normal blood glucose levels, leading to hyperinsulinemia

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Thats what happened to 45-year-old Mark, a construction supervisor

While this helps you feel full longer, it can also slow digestion and make bowel movements less frequent

In the open-label, multicenter study, patients with SAH (MDF 32 and MELD score 35) were randomized to receive SOC with continuous ELAD therapy for 35 days or SOC alone