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The method begins with calculating the R ratio to classify the type of injury as hepatocellular, cholestatic, or mixed, based on the elevations in serum enzyme activity

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doi: 10.3389/fmed.2023.1141355 83

While the expression of DNMT3B, DNMT3L, and TET1 is barely detectable in SCD erythroblasts, the expression of DNMT1, DNMT3A, TET2 or TET3 was not significantly changed at the mRNA or protein level after DMF treatment (Supplementary Fig