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Many people find that these symptoms are mild and improve over time as their bodies adjust
In the landmark STEP 1 trial, published in the New England Journal of Medicine in 2021, patients taking semaglutide 2.4 mg (Wegovy) lost an average of 14.9% of their body weight over 68 weeks, compared to 2.4% in the placebo group
Look for signs of metabolic dysfunction, abnormal liver enzymes, and fatty liver on imaging, even in patients who appear lean
In her practice, six weeks postpartum is the absolute earliest she'd prescribe a GLP-1 (to someone who isn't breastfeeding more on nursing moms in a minute)
In these settings, Tirz has demonstrated a generally favorable safety profile , particularly at dosages typically used for research purposes
Laelago, 2018)
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