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Storage:Protected from direct light and humidity at a temperature of 35.6-46.4F (2-8C)

Sorafenib blocks systemic XC-mediated cystine input, causing endoplasmic reticulum stress, GSH depletion, and iron-dependent lipid ROS buildup (114)

This increases cell membrane permeability, leading to abnormal exchange of substances between the intracellular and extracellular environments, and leakage of cellular contents such as ATP and HMGB1DAMPsinto the extracellular environment

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The medium used for growth of strains is given for each experiment in the Figure Legends

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