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In 2025, the agency also approved it to treat a serious form of liver disease known as metabolic-associated steatohepatitis (MASH), noting Wegovy's effect on the body may improve liver inflammation and scarring
In part 1, the objective was to demonstrate that treatment with semaglutide 2.4 mg improves liver histology at 72 weeks based on biopsy sampling from the first 800 randomised patients
Given the small sample size, absence of a comparator group, lack of formal event adjudication, and limited statistical power, no conclusions regarding cardiovascular benefit or harm can be drawn
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