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doi:10.3389/fimmu.2020.568447

Prebiotic selection influencing inflammatory bowel disease treatment outcomes: a review of the preclinical and clinical evidence

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Constipation: Some users may experience the opposite problem difficulty passing stools or a reduced frequency of bowel movements

A key reason for the success of its Zepbound drug is its status as a "dual agonist." Wegovy targets only GLP-1 receptors, whereas tirzepatide (aka Zebound) targets both GLP-1 and GIP receptors, leading to greater overall weight loss