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In naturally aged mice, the renal function improvements were statistically significant but more modest a pattern consistent with the lower but still meaningful senescent cell burden in normal aging

Similarly, there was no evidence of a difference in mortality rate between the GLP-1RAs group and the SGLT2 inhibitors group (HR 1.06

Curr Opin Immunol (2001) 13(3):299306.10.1016/S0952-7915(00)00219-3 107 HibbsMLHarderKW

A single missed injection delays progress by approximately one week but does not erase previous weight loss