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The critical balancing act is this: glucagon raises blood glucose, but GLP-1R and GIPR agonism raise insulin in a glucose-dependent manner

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Sleep and stress : Target a consistent sleep window and use simple stress reduction like brief walks, breathing exercises, or social support

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Persistent nausea lasting more than 2 weeks after a dose increase warrants stepping back to the previous dose for 2 to 4 additional weeks before trying again