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This indicated that the functional inhibition of GJ proteins not only protects against APAP-induced hepatotoxicity but also effectively mitigates the increased sensitivity to APAP as seen in hepsin / mice

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For instance, certain herbal compounds alleviate depression by activating the Creb1/Six3os1 axis or modulating the GhrlEdn1/Mecp2/P-mTOR/VEGFA pathway [536, 537]