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They are hard limits backed by stability data

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These complications may be attributed to nutritional deficiencies frequently observed during rapid weight loss, including depletion of iron, vitamin B 12 , fat-soluble vitamins, and proteins

However, dedicated cardiovascular outcomes trials (CVOTs) for retatrutide have not yet been completed , and it is not yet confirmed whether a CVOT is registered as part of the current TRIUMPH Phase 3 programme