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Loren Pickart, who isolated GHK-CU in 1973, shows that the peptide increases production of Type I and Type III collagen while simultaneously upregulating matrix metalloproteinases, the enzymes that break down old, damaged collagen

CCL18, CCL19, CCL20, CCL21, CCL25, CCR5, and CCR6 recruit T cells into the joint

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Localized burning and itching usually subside with elevation and warm compresses

GHK-Cu is a cosmetic product and not FDA-approved for treating hair loss

Notoginsenoside R1 promoted HO-1 expressions to reduce oxidative stress-induced apoptosis and kidney fibrosis in HK-2 cells and C57BL/6J mice [146]