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Hydroxycarbamide in very young children with sickle-cell anaemia: a multicentre, randomised, controlled trial (BABY HUG)

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Goodnick PJ

In certain cases, it is very difficult to distinguish whether oxidative stress is the cause or an effect of cellular damage

Another Nrf2-regulated protein is the stress responsive inducible enzyme heme oxygenase 1 (HO-1), which metabolizes prooxidant heme to the antioxidant pigment biliverdin, ferrous iron and carbon monoxide 8