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Importantly, its mechanism is complementary to GLP-1 receptor agonists, making it an attractive candidate for combination therapy

PMID: 39741578

Environmental risk factors of glutathione deficiency include: Exposure to chemical toxins (including pollution) UV radiation exposure Cadmium exposure Chronic stress Excessive alcohol use Smoking Poor diet Certain medications (like Tylenol) Certain illnesses are known to decrease glutathione levels

It has also received approval for chronic weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity, as an adjunct to reduced-calorie diet and increased physical activity

10.1002/mds.23263 36 CastelloP