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Abstract The discovery of intrinsically disordered proteins (IDPs) (and, therefore, the establishment of the field of protein intrinsic disorder) was initially driven by low-resolution techniques, which overturned the established lock-and-key paradigm of structural biology by showing that some proteins exist as a dynamic conformational ensemble rather than a single fixed structure

Neurologic deficits were assessed, and the rats were sacrificed at 24 h after cerebral I/R surgery to measure brain infarct sizes

Overall, this data suggests BPA exposure can target non-genomic signaling pathways in retina, providing a potential mechanism underlying its long-term effects, especially at low concentrations

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