This may be similar to patients with diabetes with lower HbA1c having less change than those with higher HbA1c with anti-diabetes medications which dont cause hypoglycemia
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To overcome these limitations, in this study, we describe the rational design, synthesis, and in-depth biological assessment of ruthenium (Ru)-containing nanoreactors for the catalytic oxidation of GSH to GSSG in hypoxic osteosarcoma
Jian D, Jiang D, Su J, Chen W, Hu X, Kuang Y
Furthermore, balancing the therapeutic window requires integrating pharmacologic co-therapies, carefully calibrated frequency-intensity matrices, and longitudinal safety surveillance, particularly in advanced cases such as castration-resistant disease