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EC 028 EC0048 EC0049: MS ESI, [M+H] + ) 795

Through a system involving the enzymes carnitine palmitoyltransferase I (CPT-I) and carnitine palmitoyltransferase II (CPT-II), L-carnitine binds to fatty acid molecules, transports them into the mitochondrial matrix, and releases them for beta-oxidation, the process that breaks fatty acids down into acetyl-CoA units for energy production in the citric acid cycle

Gut microbiome features were identified to establish a TMAO producer prediction model Because of the distinct microbial profiles for different TMAO productivities, we then search to find signatures that could help predict TMAO producer phenotypes

Carnitine for this reaction can be biosynthesized or obtained from dietary sources and further transported via the organic cation novel type 2 transporter (OCTN2) [75, 107, 122]

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The results showed no significant differences in the blood level of these biomarkers after the intervention