As women approach menopause, levels of key hormones like estrogen, progesterone and testosterone begin to fluctuate and then decline significantly
For instance, curcumin has been shown to upregulate thyroid-specific transcription factors (TTF-1, TTF-2, PAX8) and restore NIS protein expression, thereby overcoming radioiodine (RAI) resistance and enhancing RAI therapy efficacy, offering new perspectives for thyroid cancer treatment (148, 149)
10.1007/s00774-020-01191-1 74 TanakaS
Cz prac trudno jednoznacznie zweryfikowa w bazach PubMed/DOI
Abbreviations CD: Crohns disease DPP-IV: Dipeptidyl peptidase IV DSS: Dextran sulfate sodium EEC: Enteroendocrine cells GI: Gastrointestinal tract GIP: Gastro-insulinotropic peptide GLP: Glucagon-like peptide GM-CSF: Granulocyte-macrophage colony-stimulating factor IBD: Inflammatory bowel diseases IFN-: Interferon IGF-1: Insulin-like growth factor 1 IL: Interleukin LPS: Lipopolysaccharide PC 1/3: Prohormone convertase 1/3 PEG: Polyethylene glycosyl SCFA: Short-chain fatty acids TNBS: 2,4,6-trinitrobenzenesulfonic acid TNF-: Tumor necrosis factor UC: Ulcerative colitis References Abrahami D, Douros A, Yin H, et al (2018) Dipeptidyl peptidase-4 inhibitors and incidence of inflammatory bowel disease among patients with type 2 diabetes: population based cohort study
The similarities in disease mechanisms across species are striking, and as a result, many veterinary drugs used to treat animals are either identical or closely related to those used for human treatment
