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In modellen van humane dermale fibroblasten verhogen concentraties van 1 tot 10 M de productie van type I-collageen met 70% (Campbell et al., 2012, DOI: 10.1155/2012/431024)

To construct the shRNA knockdown vector pLKO.1-GST DAF , we inserted the GST-EGFP-GPI DAF coding region into the pLKO.1 puro plasmid in place of the puromycin resistance gene