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doi: 10.3389/fphar.2022.814871 104 LiuH.WangJ.TaoY.LiX.QinJ.BaiZ.et al

Science 261:466469 Keller J, Beglinger C, Holst JJ, Andresen V, Layer P (2009) Mechanisms of gastric emptying disturbances in chronic and acute inflammation of the distal gastrointestinal tract

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Gently swirl or roll the vial to help the drug dissolve do not violently shake unless instructed, as some drugs can be denatured by shaking

First published in February 1922, their results were heralded as a major achievement and transformed the treatment of diabetes (Diem, Ducluzeau, Scheen